Biomedicine meets data science | Bioinformatician & Molecular biologist | Consulting, Research, Service
Aktualisiert am 09.03.2026
Profil
Freiberufler / Selbstständiger
Remote-Arbeit
Verfügbar ab: 07.06.2026
Verfügbar zu: 80%
davon vor Ort: 25%
Bioinformatics
Molecular Biology
Data Science
Bioinformatician
Next-generation sequencing
Transcriptomics
Epigenetics
Proteomics
R
Python
Bash
Biological Data Analysis
Computational Biology
Research
Data Analytics
Immunology
Neuroscience
Biology
Project management
Teamwork
Science
single cell
transcriptomics
English
Verhandlungssicher
German
Muttersprache
Dutch
Grundkenntnisse

Einsatzorte

Einsatzorte

Hamburg (+500km)
Deutschland
möglich

Projekte

Projekte

3 years 9 months
2022-06 - now

Immune development in human intestine

multiomics (single-cell mRNA/VDJ spatial- and bulk transcriptomics) high-dimensional fl ow cytometry
  • Project lead, collaborating with 3 scientists, implementing omics technologies
  • Managing a large budget for omics applications
  • Expected outcome: developmental atlas of human intestinal immune cells
multiomics (single-cell mRNA/VDJ spatial- and bulk transcriptomics) high-dimensional fl ow cytometry
Research Group Immune ontogeny, Leibniz-Institute of Virology
1 year 9 months
2023-02 - 2024-10

High-dimensional fl ow cytometry analysis pipeline

  • Developing a pipeline to analyse high-dimensional fl ow cytometry data in R using existing machine learning algorithms and Bioconductor tools
  • Outcome: 
    • ?User-friendly R toolkit for cytometry data analysis (preprint at bioRxiv)
Institute Medical Systems Biology, University Medical Center, Hamburg-Eppendorf
1 year 4 months
2022-06 - 2023-09

Sex differences in antiviral immunity

single-cell mRNA sequencing (long and short read)
  • Supervising 3 scientists conducting bioinformatic analyses in 2 subprojects
  • Outcome: 
    • ?sex-specifi c genetics in antiviral response (scientifi c publication in iScience)
single-cell mRNA sequencing (long and short read)
Department of Immunology, University Medical Center, Hamburg-Eppendorf
4 years 9 months
2016-09 - 2021-05

Immune checkpoints in glial cells and multiple sclerosis

mRNA sequencing flow cytometry fl ow cytometry ...
  • Project lead managing multiple subprojects with (inter)national collaborations
  • Outcome: 
    • ?function of immune checkpoint VISTA in microglia (scientifi c publications in Glia, Journal of Molecular Medicine and Acta neuropathologica communications)
mRNA sequencing flow cytometry fl ow cytometry various laboratory techniques
Department of Neuroscience, University Medical Center Groningen
1 year 4 months
2019-03 - 2020-06

Microglia development in the human central nervous system

mRNA sequencing (bulk & single-cell) ATAC sequencing
  • Planning of project and conducting experiments and tissue collection
  • Outcome
    • ?epigenetic and transcriptomic landscape of microglia during human fetal development (scientifi c publication in Science)
mRNA sequencing (bulk & single-cell) ATAC sequencing
Department of Neuroscience, University Medical Center Groningen

Aus- und Weiterbildung

Aus- und Weiterbildung

4 years 9 months
2016-09 - 2021-05

Promotion in Neuroimmunology

Ph.D., University of Groningen, Groningen (The Netherlands)
Ph.D.
University of Groningen, Groningen (The Netherlands)
1 year 11 months
2014-09 - 2016-07

Study - Biomedical Sciences

Master of Science, University of Groningen, Groningen (The Netherlands)
Master of Science
University of Groningen, Groningen (The Netherlands)
1 year
2013-09 - 2014-08

Study - Molecular Biology

Bachelor of Science, University of Aberdeen, Aberdeen (Scotland, United Kingdom)
Bachelor of Science
University of Aberdeen, Aberdeen (Scotland, United Kingdom)
2 years
2011-09 - 2013-08

Applied Biology

Bachelor of Science, University of Applied Sciences Bonn-Rhein-Sieg, Rheinbach (Germany)
Bachelor of Science
University of Applied Sciences Bonn-Rhein-Sieg, Rheinbach (Germany)

Kompetenzen

Kompetenzen

Top-Skills

Bioinformatics Molecular Biology Data Science Bioinformatician Next-generation sequencing Transcriptomics Epigenetics Proteomics R Python Bash Biological Data Analysis Computational Biology Research Data Analytics Immunology Neuroscience Biology Project management Teamwork Science single cell transcriptomics

Schwerpunkte

Bioinformatics

Produkte / Standards / Erfahrungen / Methoden

Profile
Data is the future of biomedicine, and I contribute to discovery and innovation by bridging biology and data science with data analysis & interpretation and development of pipelines & tools. My main focus is on omics technologies in immunology, neuroscience and developmental biology. I have 5+ years of experience in bioinformatics, biomedical research and experimental generation of omics data. As a result of my mixed background in computational- and molecular biology, I know where the data comes from and what it means.

Biomedical

  • Neuroscience, Immunology, Molecular biology, Genetics, Developmental biology

Technologies
  • Transcriptomics: Gene expression (single-cell, spatial, bulk), Non-coding RNA
  • Epigenomics: Chromatin accessibility (ATAC), DNA-protein interactions (ChIP)
  • Proteomics: Mass spectrometry, High-dimensional fl ow cytometry, CITEseq
  • Immunomics: T/B cell receptor repertoire, Cytokine profi ling
  • Integration of multiple omics approaches on single-cell and bulk level

Computational
  • R: Bioconductor, EdgeR, DESeq2, Seurat, Slingshot, Monocle, SCENIC, etc
  • Python: Scanpy, Squidpy, Scirpy, Muon, Pandas, Numpy, etc
  • Other: Nextfl ow, Docker, Git, Jupyter, Bash, Alignment tools, etc.

Employment History
10/2023 ? today
Freelance Bioinformatics Consultant
  • Collaborating with clients from academia and industry to guide and conduct omics experimental planning, and data analysis & interpretation.

08/2024 ? 11/2024
Team Lead Biomedical Data Science
University Medical Center Hamburg-Eppendorf, Germany
  • Leading a team of 5 bioinformaticians and computational biologists
  • Overseeing multidisciplinary projects of biologists and bioinformaticians
  • Guiding integration of omics data (long-read, single-cell & spatial multiomics)

06/2022 - 10/2024
(Senior) Postdoctoral Research Associate
Leibniz-Institute of Virology & University Medical Center Hamburg-Eppendorf, Germany
  • Guiding and overseeing systems immunology projects within department
  • Teaching bioinformatics course for postgraduates
  • Implementing omics laboratory protocols and bioinformatics pipelines
  • Analysing and interpreting various omics datasets related to immunity

09/2016 ? 05/2021
Doctoral Researcher
University Medical Center Groningen, The Netherlands
  • Generating NGS libraries and analysing omics data
  • Supervising 4 Master, 1 Bachelor and 1 Doctoral student
  • Presenting results at (inter)national conferences and in publications

03/2017 ? 05/2017
Visiting Scientist
Dartmouth Hitchcock Medical Center, Dartmouth College, USA
  • Implementing and conducting molecular biology experiments in the laboratory

Internship
01/2016 ? 06/2016
M. Sc. Research Intern
University Medical Center Groningen (The Netherlands)

11/2014 ? 06/2015
M. Sc. Research Intern 
University Medical Center Groningen (The Netherlands)

01/2014 ? 03/2014
B. Sc. Research Intern
University of Aberdeen (Scotland, United Kingdom)

Einsatzorte

Einsatzorte

Hamburg (+500km)
Deutschland
möglich

Projekte

Projekte

3 years 9 months
2022-06 - now

Immune development in human intestine

multiomics (single-cell mRNA/VDJ spatial- and bulk transcriptomics) high-dimensional fl ow cytometry
  • Project lead, collaborating with 3 scientists, implementing omics technologies
  • Managing a large budget for omics applications
  • Expected outcome: developmental atlas of human intestinal immune cells
multiomics (single-cell mRNA/VDJ spatial- and bulk transcriptomics) high-dimensional fl ow cytometry
Research Group Immune ontogeny, Leibniz-Institute of Virology
1 year 9 months
2023-02 - 2024-10

High-dimensional fl ow cytometry analysis pipeline

  • Developing a pipeline to analyse high-dimensional fl ow cytometry data in R using existing machine learning algorithms and Bioconductor tools
  • Outcome: 
    • ?User-friendly R toolkit for cytometry data analysis (preprint at bioRxiv)
Institute Medical Systems Biology, University Medical Center, Hamburg-Eppendorf
1 year 4 months
2022-06 - 2023-09

Sex differences in antiviral immunity

single-cell mRNA sequencing (long and short read)
  • Supervising 3 scientists conducting bioinformatic analyses in 2 subprojects
  • Outcome: 
    • ?sex-specifi c genetics in antiviral response (scientifi c publication in iScience)
single-cell mRNA sequencing (long and short read)
Department of Immunology, University Medical Center, Hamburg-Eppendorf
4 years 9 months
2016-09 - 2021-05

Immune checkpoints in glial cells and multiple sclerosis

mRNA sequencing flow cytometry fl ow cytometry ...
  • Project lead managing multiple subprojects with (inter)national collaborations
  • Outcome: 
    • ?function of immune checkpoint VISTA in microglia (scientifi c publications in Glia, Journal of Molecular Medicine and Acta neuropathologica communications)
mRNA sequencing flow cytometry fl ow cytometry various laboratory techniques
Department of Neuroscience, University Medical Center Groningen
1 year 4 months
2019-03 - 2020-06

Microglia development in the human central nervous system

mRNA sequencing (bulk & single-cell) ATAC sequencing
  • Planning of project and conducting experiments and tissue collection
  • Outcome
    • ?epigenetic and transcriptomic landscape of microglia during human fetal development (scientifi c publication in Science)
mRNA sequencing (bulk & single-cell) ATAC sequencing
Department of Neuroscience, University Medical Center Groningen

Aus- und Weiterbildung

Aus- und Weiterbildung

4 years 9 months
2016-09 - 2021-05

Promotion in Neuroimmunology

Ph.D., University of Groningen, Groningen (The Netherlands)
Ph.D.
University of Groningen, Groningen (The Netherlands)
1 year 11 months
2014-09 - 2016-07

Study - Biomedical Sciences

Master of Science, University of Groningen, Groningen (The Netherlands)
Master of Science
University of Groningen, Groningen (The Netherlands)
1 year
2013-09 - 2014-08

Study - Molecular Biology

Bachelor of Science, University of Aberdeen, Aberdeen (Scotland, United Kingdom)
Bachelor of Science
University of Aberdeen, Aberdeen (Scotland, United Kingdom)
2 years
2011-09 - 2013-08

Applied Biology

Bachelor of Science, University of Applied Sciences Bonn-Rhein-Sieg, Rheinbach (Germany)
Bachelor of Science
University of Applied Sciences Bonn-Rhein-Sieg, Rheinbach (Germany)

Kompetenzen

Kompetenzen

Top-Skills

Bioinformatics Molecular Biology Data Science Bioinformatician Next-generation sequencing Transcriptomics Epigenetics Proteomics R Python Bash Biological Data Analysis Computational Biology Research Data Analytics Immunology Neuroscience Biology Project management Teamwork Science single cell transcriptomics

Schwerpunkte

Bioinformatics

Produkte / Standards / Erfahrungen / Methoden

Profile
Data is the future of biomedicine, and I contribute to discovery and innovation by bridging biology and data science with data analysis & interpretation and development of pipelines & tools. My main focus is on omics technologies in immunology, neuroscience and developmental biology. I have 5+ years of experience in bioinformatics, biomedical research and experimental generation of omics data. As a result of my mixed background in computational- and molecular biology, I know where the data comes from and what it means.

Biomedical

  • Neuroscience, Immunology, Molecular biology, Genetics, Developmental biology

Technologies
  • Transcriptomics: Gene expression (single-cell, spatial, bulk), Non-coding RNA
  • Epigenomics: Chromatin accessibility (ATAC), DNA-protein interactions (ChIP)
  • Proteomics: Mass spectrometry, High-dimensional fl ow cytometry, CITEseq
  • Immunomics: T/B cell receptor repertoire, Cytokine profi ling
  • Integration of multiple omics approaches on single-cell and bulk level

Computational
  • R: Bioconductor, EdgeR, DESeq2, Seurat, Slingshot, Monocle, SCENIC, etc
  • Python: Scanpy, Squidpy, Scirpy, Muon, Pandas, Numpy, etc
  • Other: Nextfl ow, Docker, Git, Jupyter, Bash, Alignment tools, etc.

Employment History
10/2023 ? today
Freelance Bioinformatics Consultant
  • Collaborating with clients from academia and industry to guide and conduct omics experimental planning, and data analysis & interpretation.

08/2024 ? 11/2024
Team Lead Biomedical Data Science
University Medical Center Hamburg-Eppendorf, Germany
  • Leading a team of 5 bioinformaticians and computational biologists
  • Overseeing multidisciplinary projects of biologists and bioinformaticians
  • Guiding integration of omics data (long-read, single-cell & spatial multiomics)

06/2022 - 10/2024
(Senior) Postdoctoral Research Associate
Leibniz-Institute of Virology & University Medical Center Hamburg-Eppendorf, Germany
  • Guiding and overseeing systems immunology projects within department
  • Teaching bioinformatics course for postgraduates
  • Implementing omics laboratory protocols and bioinformatics pipelines
  • Analysing and interpreting various omics datasets related to immunity

09/2016 ? 05/2021
Doctoral Researcher
University Medical Center Groningen, The Netherlands
  • Generating NGS libraries and analysing omics data
  • Supervising 4 Master, 1 Bachelor and 1 Doctoral student
  • Presenting results at (inter)national conferences and in publications

03/2017 ? 05/2017
Visiting Scientist
Dartmouth Hitchcock Medical Center, Dartmouth College, USA
  • Implementing and conducting molecular biology experiments in the laboratory

Internship
01/2016 ? 06/2016
M. Sc. Research Intern
University Medical Center Groningen (The Netherlands)

11/2014 ? 06/2015
M. Sc. Research Intern 
University Medical Center Groningen (The Netherlands)

01/2014 ? 03/2014
B. Sc. Research Intern
University of Aberdeen (Scotland, United Kingdom)

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