Bioinformatics, webdesign, digital transformation, cloud computing, data science, data analysis
Aktualisiert am 19.03.2025
Profil
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Remote-Arbeit
Verfügbar ab: 17.03.2025
Verfügbar zu: 100%
davon vor Ort: 100%
Bioinformatics
Webdesign
Cloud Computing
Big Data Analytics
Big data management
Multi-Omics data analytics
Data mining
Machine Learning
Deep Learning
data
SQL
AWS
Google Cloud
MS Azure SQL Database
Web Application
Git
Bitbucket
Docker
Product Management
MS Power BI
Atlassian JIRA Agile
Datenmanagement
German
English
Persian
Arabic
French

Einsatzorte

Einsatzorte

Deutschland, Schweiz, Österreich
möglich

Projekte

Projekte

3 years 5 months
2021-08 - 2024-12

Development of a sophisticated pipeline as a bioconductor package

DATA SCIENTIST in DRUG DISCOVERY
DATA SCIENTIST in DRUG DISCOVERY
  • Developed a sophisticated pipeline as Bioconductor package to prioritize therapeutics target identification , supporting disease-centric workflows
  • Led the design and development of an advanced in-house product for module annotation in visualization user interface app
  • Utilized advanced bioinformatics tools to facilitate the assessment of safety, druggability and various characteristics of targeting compounds.
  • Demonstrated framework of alternative splicing based classifier, identified 10 intron retention events for CMS subtyping.
  • Succeeded on multi-omics data processing and curation of clinical data, analysis of various omics data such as transcriptome, genome, whole proteome and lipidome on various cancer entities including CRC, NSCLC, breast, kidney, ovarian, bladder, prostate and liver.
  • Collaborated effectively within cross-functional teams to identify and implement innovative digital solutions, leveraging AI and machine learning for precise drug discovery.
IndivumedTherapeutics, Hamburg
2 years
2019-08 - 2021-07

Validation of the IDH mutation pattern

POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
  • Validated the IDH mutations pattern behind primary and secondary astrocytoma and oligodendroglioma, characterized a wide range of genetic alterations due to grades of glioma, identified novel biomarkers in proliferation and immune checkpoints
  • Studied the association between AML relapse after bone marrow transplantation and dysregulation of adaptive immunity pathways elements. Identified the top significant factors on recurrence pattern
  • Demonstrated a novel approach on optimizing the neural network to infer gene regulatory networks from scRNA-seq data through variational autoencoder
German Cancer Research Center(DKFZ), NCT, IMB, Dresden
1 year 7 months
2017-04 - 2018-10

Analysis of libraries with targeted active ingredient screening

POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
  • Analyzed targeted drug screening libraries, identified 7 kinase inhibitor compounds that effectively regulate pHGG cancer cell proliferation
  • Characterized the molecular landscape of various K27M-driven tumorigenesis by employment the state-of-the-art ribosome and epigenome profiling
  • Studied master regulators of survival after DAXX knockdown underlying APL pathogenesis by using cutting-edge techniques in transcriptome and methylome levels
  • Identified synaptic plasticity and epigenetic alterations that drive the progression of tumorigenesis among various PML overexpression and mutant mouse models
German Centerfor Neurodegenerative Diseases (DZNE), Bonn
5 years 1 month
2012-09 - 2017-09

three research projects

PHD in LIFESCIENCE - BIOINFORMATICS
PHD in LIFESCIENCE - BIOINFORMATICS
  • Opened a new framework to obtain a systematic picture for the reshaped central backbone of defense signaling during infection progression with DNA and RNA viruses.
  • Designed and managed three research projects, highly independently. Succeeded on data processing, analysis, visualization and interpretation of time-series dual-RNAseq, metabolome, metabolic network, flux balance analysis, RT-PCRs, TAS-ELISA, and oxidative activity assessments.
  • Characterized and validated the correlation between gradient stage of infection and signaling pathways, protein synthesis, glycolysis flux distributions, oxidative activity also Rx signalosome compartments
  • Presented the results at various scientific events, including one of the world?s largest genomics conferences (PAG XXIV, San Diego, CA, 2016). Received excellent feedback.
  • Collaborated in publishing a book in Big Data Analytics in Genomics with my colleagues and supervisor. Received excellent feedback.
Leibniz-InstituteDSMZ andJulius-Maximilians-University, Würzburg
1 year 9 months
2010-10 - 2012-06

product management

TEAM LEAD - MOLECULAR BIOLOGY
TEAM LEAD - MOLECULAR BIOLOGY
  • Led product management, QC, R&D and costumer service
  • Directed cross-functional teams to implement quality-driven laboratory workflows, achieving full compliance with GMP and ISO 9001 standards
  • Led the development and launch of 10 innovative products including rapid diagnostic test kits and extraction supplements to support Molecular Biology laboratories and clinical facilities
CinnaGen Co, Tehran (Iran)
1 year 1 month
2009-09 - 2010-09

Teaching activity

TEACHER and WORKSHOP INSTRUCTOR
TEACHER and WORKSHOP INSTRUCTOR
  • Succeeded on teaching to master and PhD students in Biotechnology methods
  • Conducted impactful multiple workshops on Genetic Engineering and Molecular Biology to clinicians and medical students enhancing their research efficiency and outcomes
University of Tehran, Tehran (Iran)
1 year 1 month
2009-09 - 2010-09

Customer support and training

APPLICATION SCIENTIST ? BIOINFORMATICS
APPLICATION SCIENTIST ? BIOINFORMATICS
  • Provided efficient costumer support and training to deliver guidance to users also troubleshoot issues related to software installation, performance and data interpretation
  • Collaborated closely with sales and marketing teams to create tailored product presentation
  • Consulted with clients to integrate bioinformatics solutions into their research or clinical workflow
Persian Bioinformatics, Tehran (Iran)

Aus- und Weiterbildung

Aus- und Weiterbildung

5 years 3 months
2012-07 - 2017-09

Promotion

PhD in Boinformatics, Julius-Maximilians-University, Würzburg
PhD in Boinformatics
Julius-Maximilians-University, Würzburg
Thesis title: on request
3 years 1 month
2006-09 - 2009-09

Study - Biotechnology

Master of Science, University of Tehran (1st ranked university in the country)
Master of Science
University of Tehran (1st ranked university in the country)
Thesis title: on request
4 years 1 month
2002-09 - 2006-09

Study - Plant Pathology

Bachelor of Science, University of Tabriz (top ranked university in the country)
Bachelor of Science
University of Tabriz (top ranked university in the country)
4 years 1 month
1998-09 - 2002-09

School Diploma

National Organization Development of Exceptional Talents (NODET)
National Organization Development of Exceptional Talents (NODET)

Position

Position

BIOINFORMATICIAN, DATA ANALYST

Kompetenzen

Kompetenzen

Top-Skills

Bioinformatics Webdesign Cloud Computing Big Data Analytics Big data management Multi-Omics data analytics Data mining Machine Learning Deep Learning data SQL AWS Google Cloud MS Azure SQL Database Web Application Git Bitbucket Docker Product Management MS Power BI Atlassian JIRA Agile Datenmanagement

Produkte / Standards / Erfahrungen / Methoden

Profile
I am a resilient life scientist with a great passion for data analysis and core competence in leadership and innovation. I have gained cross-disciplinary experience in a wide range of transnational research spanning plant virology lab to advanced analytics in clinical oncology, immunology and therapeutic target discovery. With the proven skills to bridge the gap between technical and business teams, I would love to streamline data-driven processes, and work closer to impactful insights in science.

Skills
  • Bioinformatics
  • Big data management
  • Multi-Omics data analytics
  • Pipeline development
  • Data mining and Machine Learning
    • Caret, tidymodels, Scikit-learn
  • Deep learning
    • ANN, CNN, RNN
  • non-parametric statistics
  • Data visualization
  • Data annotation
  • Pathway enrichment analysis
  • Data engineering
    • SQL
  • Cloud computing
    • AWS
  • Web app development
    • Shiny
    • Dash
  • Versioning systems
    • git
  • Containerization
    • Docker
  • Data-driven decision making
  • Problem solving
  • Cross-functional teams 
  • communication
  • Product management
  • Microsoft Office PowerBI
  • Scrum ceremonies
    • JIRA
    • Youtrack
  • Leadership
  • People management
  • Project management
  • Creativity, ingenuity, originality
  • adoptability
  • holistic, criticalthinking

Programmiersprachen

R
Bash
Python

Einsatzorte

Einsatzorte

Deutschland, Schweiz, Österreich
möglich

Projekte

Projekte

3 years 5 months
2021-08 - 2024-12

Development of a sophisticated pipeline as a bioconductor package

DATA SCIENTIST in DRUG DISCOVERY
DATA SCIENTIST in DRUG DISCOVERY
  • Developed a sophisticated pipeline as Bioconductor package to prioritize therapeutics target identification , supporting disease-centric workflows
  • Led the design and development of an advanced in-house product for module annotation in visualization user interface app
  • Utilized advanced bioinformatics tools to facilitate the assessment of safety, druggability and various characteristics of targeting compounds.
  • Demonstrated framework of alternative splicing based classifier, identified 10 intron retention events for CMS subtyping.
  • Succeeded on multi-omics data processing and curation of clinical data, analysis of various omics data such as transcriptome, genome, whole proteome and lipidome on various cancer entities including CRC, NSCLC, breast, kidney, ovarian, bladder, prostate and liver.
  • Collaborated effectively within cross-functional teams to identify and implement innovative digital solutions, leveraging AI and machine learning for precise drug discovery.
IndivumedTherapeutics, Hamburg
2 years
2019-08 - 2021-07

Validation of the IDH mutation pattern

POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
  • Validated the IDH mutations pattern behind primary and secondary astrocytoma and oligodendroglioma, characterized a wide range of genetic alterations due to grades of glioma, identified novel biomarkers in proliferation and immune checkpoints
  • Studied the association between AML relapse after bone marrow transplantation and dysregulation of adaptive immunity pathways elements. Identified the top significant factors on recurrence pattern
  • Demonstrated a novel approach on optimizing the neural network to infer gene regulatory networks from scRNA-seq data through variational autoencoder
German Cancer Research Center(DKFZ), NCT, IMB, Dresden
1 year 7 months
2017-04 - 2018-10

Analysis of libraries with targeted active ingredient screening

POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
POSTDOCTORAL-RESEARCHER in BIOINFORMATICS
  • Analyzed targeted drug screening libraries, identified 7 kinase inhibitor compounds that effectively regulate pHGG cancer cell proliferation
  • Characterized the molecular landscape of various K27M-driven tumorigenesis by employment the state-of-the-art ribosome and epigenome profiling
  • Studied master regulators of survival after DAXX knockdown underlying APL pathogenesis by using cutting-edge techniques in transcriptome and methylome levels
  • Identified synaptic plasticity and epigenetic alterations that drive the progression of tumorigenesis among various PML overexpression and mutant mouse models
German Centerfor Neurodegenerative Diseases (DZNE), Bonn
5 years 1 month
2012-09 - 2017-09

three research projects

PHD in LIFESCIENCE - BIOINFORMATICS
PHD in LIFESCIENCE - BIOINFORMATICS
  • Opened a new framework to obtain a systematic picture for the reshaped central backbone of defense signaling during infection progression with DNA and RNA viruses.
  • Designed and managed three research projects, highly independently. Succeeded on data processing, analysis, visualization and interpretation of time-series dual-RNAseq, metabolome, metabolic network, flux balance analysis, RT-PCRs, TAS-ELISA, and oxidative activity assessments.
  • Characterized and validated the correlation between gradient stage of infection and signaling pathways, protein synthesis, glycolysis flux distributions, oxidative activity also Rx signalosome compartments
  • Presented the results at various scientific events, including one of the world?s largest genomics conferences (PAG XXIV, San Diego, CA, 2016). Received excellent feedback.
  • Collaborated in publishing a book in Big Data Analytics in Genomics with my colleagues and supervisor. Received excellent feedback.
Leibniz-InstituteDSMZ andJulius-Maximilians-University, Würzburg
1 year 9 months
2010-10 - 2012-06

product management

TEAM LEAD - MOLECULAR BIOLOGY
TEAM LEAD - MOLECULAR BIOLOGY
  • Led product management, QC, R&D and costumer service
  • Directed cross-functional teams to implement quality-driven laboratory workflows, achieving full compliance with GMP and ISO 9001 standards
  • Led the development and launch of 10 innovative products including rapid diagnostic test kits and extraction supplements to support Molecular Biology laboratories and clinical facilities
CinnaGen Co, Tehran (Iran)
1 year 1 month
2009-09 - 2010-09

Teaching activity

TEACHER and WORKSHOP INSTRUCTOR
TEACHER and WORKSHOP INSTRUCTOR
  • Succeeded on teaching to master and PhD students in Biotechnology methods
  • Conducted impactful multiple workshops on Genetic Engineering and Molecular Biology to clinicians and medical students enhancing their research efficiency and outcomes
University of Tehran, Tehran (Iran)
1 year 1 month
2009-09 - 2010-09

Customer support and training

APPLICATION SCIENTIST ? BIOINFORMATICS
APPLICATION SCIENTIST ? BIOINFORMATICS
  • Provided efficient costumer support and training to deliver guidance to users also troubleshoot issues related to software installation, performance and data interpretation
  • Collaborated closely with sales and marketing teams to create tailored product presentation
  • Consulted with clients to integrate bioinformatics solutions into their research or clinical workflow
Persian Bioinformatics, Tehran (Iran)

Aus- und Weiterbildung

Aus- und Weiterbildung

5 years 3 months
2012-07 - 2017-09

Promotion

PhD in Boinformatics, Julius-Maximilians-University, Würzburg
PhD in Boinformatics
Julius-Maximilians-University, Würzburg
Thesis title: on request
3 years 1 month
2006-09 - 2009-09

Study - Biotechnology

Master of Science, University of Tehran (1st ranked university in the country)
Master of Science
University of Tehran (1st ranked university in the country)
Thesis title: on request
4 years 1 month
2002-09 - 2006-09

Study - Plant Pathology

Bachelor of Science, University of Tabriz (top ranked university in the country)
Bachelor of Science
University of Tabriz (top ranked university in the country)
4 years 1 month
1998-09 - 2002-09

School Diploma

National Organization Development of Exceptional Talents (NODET)
National Organization Development of Exceptional Talents (NODET)

Position

Position

BIOINFORMATICIAN, DATA ANALYST

Kompetenzen

Kompetenzen

Top-Skills

Bioinformatics Webdesign Cloud Computing Big Data Analytics Big data management Multi-Omics data analytics Data mining Machine Learning Deep Learning data SQL AWS Google Cloud MS Azure SQL Database Web Application Git Bitbucket Docker Product Management MS Power BI Atlassian JIRA Agile Datenmanagement

Produkte / Standards / Erfahrungen / Methoden

Profile
I am a resilient life scientist with a great passion for data analysis and core competence in leadership and innovation. I have gained cross-disciplinary experience in a wide range of transnational research spanning plant virology lab to advanced analytics in clinical oncology, immunology and therapeutic target discovery. With the proven skills to bridge the gap between technical and business teams, I would love to streamline data-driven processes, and work closer to impactful insights in science.

Skills
  • Bioinformatics
  • Big data management
  • Multi-Omics data analytics
  • Pipeline development
  • Data mining and Machine Learning
    • Caret, tidymodels, Scikit-learn
  • Deep learning
    • ANN, CNN, RNN
  • non-parametric statistics
  • Data visualization
  • Data annotation
  • Pathway enrichment analysis
  • Data engineering
    • SQL
  • Cloud computing
    • AWS
  • Web app development
    • Shiny
    • Dash
  • Versioning systems
    • git
  • Containerization
    • Docker
  • Data-driven decision making
  • Problem solving
  • Cross-functional teams 
  • communication
  • Product management
  • Microsoft Office PowerBI
  • Scrum ceremonies
    • JIRA
    • Youtrack
  • Leadership
  • People management
  • Project management
  • Creativity, ingenuity, originality
  • adoptability
  • holistic, criticalthinking

Programmiersprachen

R
Bash
Python

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